Latest Research
Omega-3s, ApoE Genotype and Cognitive Decline
The most recent statistics indicate that dietary intake of omega-3 PUFA is insufficient in >95% of Americans. Deficits in omega-3s have been shown to contribute to inflammatory signaling, apoptosis, and neuronal dysfunction in all cause dementia, including Alzheimer's disease. DHA (22:6[n-3]), …read more
Improvements in Nutrition and Lifestyle Increase Telomerase Activity
Telomeres, the protective DNA–protein complexes at the end of chromosomes, are required for DNA replication and to protect chromosomes from nuclease degradation, end-to-end fusion, and the initiation of cellular senescence. Since telomeres shorten with each cell division, telomere length is a …read more
y-Tocopherol, but Not a-Tocopherol, Improves Anti-Inflammatory; Decreases Adverse Effects of Aspirins
Nonsteriodal anti-inflammatory drugs (NSAIDs), including aspirin, are commonly used for pain relief, have consistently been shown to reduce the risk of cancers, and low-dose aspirin is effective in reducing cardiovascular disease risk because of its antithrombotic effect. However, the long-term use …read more
Slowing Telomere Attrition and Cellular Senescence—Today: Part II
Cellular senescence, although protective when triggered in cells that have become cancerous, plays a key pathological role in other age-associated diseases and in so-called "healthy aging." The age-associated increase in cellular senescence has been assumed to result from the cumulative effects …read more
Slowing Telomere Attrition and Cellular Senescence—Today: Part I
Cellular senescence, although protective when triggered in cells that have become cancerous, plays a key pathological role in other age-associated diseases and in so-called "healthy aging." The age-associated increase in cellular senescence has been assumed to result from the cumulative effects …read more
Daily Omega-3 Supplement, But Not Statin, Benefits Chronic Heart Failure Patients
Omega-3 fatty acid supplements, but not statin drugs, can help patients with chronic heart failure, show two parallel studies conducted for the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico Heart Failure (GISSI-HF) trial and released for early online publication …read more
Beyond α-Tocopherol: A Review of Natural Vitamin E’s Therapeutic Potential in Human Health and Disease: Part II
In Part I of this article, evidence from a wide range of peer-reviewed research, including in vitro and in vivo studies, clinical and randomized controlled trials, epidemiological studies, meta-analyses and reviews, was presented. The case was made that while decreased chronic …read more
Beyond α-Tocopherol: A Review of Natural Vitamin E’s Therapeutic Potential in Human Health and Disease: Part I
A widely reported meta-analysis, published in the Annals of Internal Medicine in 2005, found that, while doses of vitamin E < 200 IU had no negative effects, high-dose vitamin E, defined as ≥ 400 IU per day, resulted in a small …read more
Alzheimer’s Disease: a 21st Century Epidemic
Accumulation of amyloid plaque is a common feature not only in Alzheimer's disease (AD), Creutzfeldt-Jakob Disease (aka Mad Cow disease), and the dementias associated with Parkinson’s disease and Huntington’s disease, but in the aging brain, brain injury, and certain chronic low …read more
Advanced Glycated End-products (AGEs)
Advanced glycated end-products (AGEs) form as a result of a non-enzymatic reaction in which glucose forms adducts with proteins, lipids and nucleic acids. AGEs accumulate naturally as a result of chronological aging, but this process is greatly accelerated under conditions of …read more
Lara Pizzorno is a member of the American Medical Writers Association with 25+ years of experience writing for physicians and the public, Lara is Managing Editor for Longevity Medicine Review as well as Senior Medical Editor for SaluGenecists, Inc. Read more...
Lara Pizzorno, MDiv, MA, LMT
John Morgenthaler has been active in the field of nutritional medicine since 1986. Today, John travels the world looking for breakthrough nutraceuticals and anti-aging therapies. He also continues to publish cutting-edge nutrition and medical science books and periodicals. Read more...
John Morgenthaler, Publisher
