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I thought you'd enjoy this article by Lara Pizzorno, MDiv, MA, LMT on Longevity Medicine Review:

http://www.lmreview.com/articles/view/management-of-adult-growth-hormone-deficiency-safe-and-effective

Progressive pituitary hormone deficiency is characteristic of aging, and the hypothalamic-GH-IGF-I axis is the first hormonal system affected. Daily GH secretion peaks around puberty, begins to decline by age 21, and by age 60, most adults have total 24-hour GH secretion rates indistinguishable from those of hypopituitary patients with organic lesions in the pituitary gland. Aging adults, even those receiving hormone replacement therapy with DHEA, thyroxine and sex steroids, frequently still report fatigue, lethargy, and decreased strength and exercise tolerance. Several recent epidemiologic studies indicate increased risk of cardiovascular morbidity and mortality in this population. A significant body of research suggests adult GH deficiency (AGHD) plays a key role in these age-associated health issues, and that therapy that restores GH to mid-normal ranges can successfully and safely ameliorate them. This article summarizes key studies documenting AGHD syndrome, the beneficial effects of GH therapy, the question of whether promoting activity in the GH-IGF axis increases risk of cancer and insulin resistance, and the efficacy of oral GH-releasing agents.

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Lara Pizzorno is a member of the American Medical Writers Association with 25+ years of experience writing for physicians and the public, Lara is Managing Editor for Longevity Medicine Review as well as Senior Medical Editor for SaluGenecists, Inc. Read more...

Lara Pizzorno, MDiv, MA, LMT

John Morgenthaler has been active in the field of nutritional medicine since 1986. Today, John travels the world looking for breakthrough nutraceuticals and anti-aging therapies. He also continues to publish cutting-edge nutrition and medical science books and periodicals. Read more...

John Morgenthaler, Publisher

Longevity Medicine Review - Analyzing the latest research in longevity science

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